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Sexual stimulation that causes an erection causes the production and launch of nitric oxide during the penis. Nitric oxide results in an enzyme, guanylate cyclase, to generate cyclic guanosine monophosphate (cGMP) that is principally accountable for expanding and decreasing the dimensions of blood vessels carrying blood to and with the penis and resulting in an erection.

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At doses higher than the suggested dose assortment, adverse reactions have been just like All those in-depth in Desk one underneath but commonly ended up documented far more regularly.

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